Coronary artery disease: This results from plaque buildup in your coronary arteries. The buildup causes the arteries to narrow, restricting blood flow to the heart. People living with obesity tend to have higher cholesterol levels, leading to plaque buildup. Arrhythmia or abnormal heart rhythms: Electrical conduction issues within the heart occur more frequently when the heart is damaged by coronary artery disease or other cardiac disorders. Heart failure: This occurs when the heart is severely weakened due to a heart attack, coronary artery disease, or other conditions that overwork the heart. Heart attack: This can happen when the heart muscles are starved of oxygen due to narrowed or hardened artery walls or blood clots. Vascular disease: Vascular diseases such as peripheral artery disease or aneurysms can occur due to high blood pressure and the hardening of arteries outside the heart.